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Articles by Samuel VT
PLA2G16 expression predicts prognosis and gemcitabine sensitivity in patients with pancreatic cancer
All reagents and experimental instruments used in this study are listed in Tables S1 and S2, respectively. To investigate the impact of PLA2G16 expression on pancreatic cancer patients, we acquired a pancreatic cancer patient dataset comprising clinical information and gene expression profiles from the publicly accessible repository, The Cancer Genome Atlas (TCGA) (Blum, Wang & Zenklusen, 2018).
A cost-effective predictive tool for AFP-negative focal hepatic lesions of retrospective study: enhancing clinical triage and decision-making
A cost-effective predictive tool for AFP-negative focal hepatic lesions of retrospective study: enhancing clinical triage and decision-making 1Department of Laboratory Medicine, Peking University Shenzhen Hospital, Shenzhen, Guangdong Province, China 2Department of Laboratory Medicine, JingNing People’s Hospital, Pingliang, Gansu Province, China DOI 10.7717/peerj.19150 Academic Editor Sonia Oliveira Subject Areas Gastroenterology and Hepatology, Oncology Keywords Alpha-fetal protein (AFP),...
Cholecystectomy and risk of cardiovascular disease, all-cause and cause-specific mortality: a systematic review and updated meta-analysis
In our study, cholecystectomy was not associated with the overall development of CVD, as well as CHD. In subgroup analysis, cholecystectomy increased CVD risk compared with non-gallstone controls but lowered risk compared with gallstone patients. Besides, increase in risk were observed for all-cause and cardiovascular mortality, but not for cancer mortality. These results raised concern for surveillance strategies following cholecystectomy.
Are dietary factors associated with cardiometabolic risk factors in patients with non-alcoholic fatty liver disease?
The results of this study provide valuable insights into the relationship between dietary indices and various metabolic and anthropometric parameters in participants with diverse levels of DII, DIL, DGI, and DGL. These findings contribute to the growing body of literature examining the impact of dietary factors on metabolic health, particularly in the context of NAFLD and cardiometabolic disorders.
Profile of the bile acid FXR-FGF15 pathway in the glucolipid metabolism disorder of diabetic mice suffering from chronic stress
Male 5-week-old C57BL/6 mice (Animal Certificate No.: SCXK (Su) 2020-0009 from Jiangsu Huachuang Sino Pharma Tech Could., Ltd., Jiangsu, China) were used in the study. All animals were raised in a standardized animal room (22 ± 2 °C, turning on lights from 6 a.m.∼6 p.m.), with free access to clean boiled water and rodent chow.
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