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San Lucas FA

As seen in: Oxford University Press (OUP)
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Articles

High prevalence of mutant KRAS in circulating exosome-derived DNA from early-stage pancreatic cancer patients

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By Lee MS, Ryan DP, San Lucas FA
| Oxford University Press (OUP)
Pancreatic ductal adenocarcinoma (PDAC) composes 85% of all pancreatic malignancies and is associated with a dismal 5-year survival of 6% [1, 2]. While cancer prevention initiatives and advances in targeted therapies have produced tangible survival improvements in breast, colon, and lung cancers, long-term PDAC survival remains poor and the nature of the disease does not readily present opportunities for screening and early detection [3–8].
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