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Articles by Sanat Mishra
A genetic platform to deconvolve efficacy and toxicity reveals the on-target effects of CDK11 inhibition in vivo
Abstract The cyclin-dependent kinase CDK11 is an understudied kinase that has been the subject of conflicting reports regarding its function in cancer. Here, we combine genetic and pharmacological approaches to demonstrate that CDK11 is a critical regulator of cancer cell survival that is required for RNA splicing and the expression of homologous recombination genes.
A LILLIPUT IN US
A tiny bliss that pumps the life of ours, Lying in the notch, it murmurs sweetly! Myocytes jostle amongst each other to supply blood, with the arteries assisting 'em forsooth! It speaks glibly in a murmuring tone, Never to take strokes so hard as goons! Its incessant hard work spreads the aura of being 'selfless' in the duties, even at a plethora! Sweet it is, forever the charm of our body, A Lilliput telling the epistemology of life! It stops, making our dears succumb to death, for it...
Non-compaction of ventricular myocardium with polycystic kidney disease with cardiogenic cerebral embolism
Non-compaction of ventricular myocardium with polycystic kidney disease with cardiogenic cerebral embolism Monu Rani1, Rajesh Rajput1, Sanat Mishra1 and Rakesh Garg2 1Department of Endocrinology and Medicine Unit, Pt. B D Sharma Postgraduate Institute of Medical Sciences, Rohtak, Haryana, India, Rohtak, India 2Internal Medicine, Pt. B D Sharma Postgraduate Institute of Medical Sciences Rohtak, Rohtak, Haryana, India Correspondence to Dr Rajesh Rajput; drrajeshrajput{at}outlook.com Abstract...
Hypocalcemic cardiomyopathy: a rare presenting manifestation of hypoparathyroidism
Unusual presentation of more common disease/injury Hypocalcemic cardiomyopathy: a rare presenting manifestation of hypoparathyroidism Neharika Saini, Sanat Mishra, Saurav Banerjee and Rajesh Rajput Department of Endocrinology and Medicine, Pandit Bhagwat Dayal Sharma University of Health Sciences, Rohtak, Haryana, India Correspondence to Dr Rajesh Rajput, drrajeshrajput{at}outlook.com Abstract Hypoparathyroidism patients present with features of hypocalcemia like carpopedal spasm, numbness...
Uncontrolled diabetes as a rare presenting cause of pituitary apoplexy
Unusual association of diseases/symptoms Uncontrolled diabetes as a rare presenting cause of pituitary apoplexy Ashima Mittal1, Sanat Mishra1, Karamvir Yadav2 and Rajesh Rajput1 1 Department of Endocrinology & Medicine Unit, Pt. B D Sharma Postgraduate Institute of Medical Sciences, Rohtak, India 2 Department of Internal Medicine, Pt. B D Sharma Postgraduate Institute of Medical Sciences, Rohtak, India Correspondence to Dr Rajesh Rajput, drrajeshrajput{at}outlook.com Abstract Pituitary...
Dandy-Walker variant with precocious puberty: a rare association
Precocious puberty is characterised by premature appearance of secondary sexual characteristics before the age of 7 years in girls and 9 years in boys. Dandy-Walker malformation comprises a spectrum of intracranial malformations of the posterior fossa. We present a case of a 7-year-old male child who has presented with features of central precocious puberty and on further evaluation has been found to have Dandy-Walker variant and secondary hypothyroidism.
Dulaglutide-induced cerebral venous thrombosis in a patient with type 2 diabetes mellitus
Contributors RR is the guide and mentor under whose guidance this group is managing patients. New thought and curiosity are imbibed each time a patient is admitted for management. VP is senior resident who supervised the progress in the management of the patient and gave his inputs from time to time. PKY managed the patient and ensured that treatment is delivered on time and in proper form. SM helped in getting investigations done on time and ensured that these are least bothersome to the patient.
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