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Sanaz Arzhangi on Muck Rack

Sanaz Arzhangi

As seen in: Nature
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Articles

Genetic contributors to premature coronary artery disease identified by whole-exome sequencing

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By Mahsa Tahmasebivand, Kaveh S. Hosseini, Marzieh Mohseni, Saeed Sadeghian, Elham Rostami, Reza Malekzadeh, Reza Najafipour, Mohammadreza Akbari, Yasser Riazalhosseini, Hossein Najmabadi, Mark Lathrop, Kimia Kahrizi, Ebrahim Shokouhian, Sanaz Arzhangi, Fatemeh Ghodratpour, Mohammadali Boroumand, Fatemeh Shokohizadeh, Hamidreza Khorram Khorshid
| Nature Verified
Abstract Coronary artery disease (CAD) is a leading global cause of mortality, with genetic predisposition conferring a more than two-fold increased risk in individuals with a family history of premature disease. This study aimed to identify rare genetic variants underlying inherited premature CAD (PCAD) in familial cases. Fifty unrelated Iranian families with early-onset familial CAD/MI were recruited.
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