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A simple pre-column derivatization method for the determination of mancozeb technical (fungicide) by reverse phase HPLC-UV

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By Narendra H. Petha, Indofil Industries Limited, Azad Nagar, Sandoz Baug P. O.
| Royal Society of Chemistry Verified
A simple and fast pre-column derivatization high performance liquid chromatographic method for the technical analysis of mancozeb was developed and validated in the present study. The mobile phase consists of a mixture of acetonitrile and 0.1% (v/v) formic acid in the proportion 60 : 40. This was found to give a sharp peak of the S-ethyl derivative of mancozeb (S-ethyl ethylene bis-dithiocarbamate) at a retention time of 9.12 minutes.
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