Sandra Mercier

Abstract Background Molecular diagnosis of neurodevelopmental disorders (NDDs) is mainly based on exome sequencing (ES), with a diagnostic yield of 31% for isolated and 53% for syndromic NDD. As sequencing costs decrease, genome sequencing (GS) is gradually replacing ES for genome-wide molecular testing. As many variants detected by GS only are in deep intronic or non-coding regions, the interpretation of their impact may be difficult.

http://orcid.org/0000-0003-1774-0286Kevin Riquin1, Bertrand Isidor1,2, Sandra Mercier1,2, Mathilde Nizon1,2, Estelle Colin3,4, Dominique Bonneau3,4, Laurent Pasquier5, Sylvie Odent5,6, http://orcid.org/0000-0001-9350-8177Xavier Maximin Le Guillou Horn7,8, Gwenaël Le Guyader7, http://orcid.org/0000-0002-5999-5300Annick Toutain9,10, Vincent Meyer11, Jean-François Deleuze11, Olivier Pichon2, Martine Doco-Fenzy1,2, Stéphane Bézieau1,2, http://orcid.org/0000-0002-5503-6292Benjamin Cogné1,2...

Episode 513: Jonny Harris and Kent Ayoungman at Old Sun College, the former residential school on Siksika Nation. Courtesy of CBC. December 5, 2019 (December 2019) – Award-winning CBC original series STILL STANDING will feature Siksika Nation, Alberta in the Season 5 finaleairing Tuesday, December 10 at 8 p.m. (8:30 NT) on CBC and the free CBC Gem streaming service. The episode was filmed in November 2018 when Canadian comedian Jonny Harris was warmly welcomed into the community.