Sara Ali Kandeel on Muck Rack

Sara Ali Kandeel

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Articles

Regulatory impact of intermittent fasting on autophagy in high fat diet induced structural and cognitive brain deteriorations in rats

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By Mohamed Aref, Nievin Ahmed Mahran, Haifa Alqahtani, Amira Hamed, Eman Elsheikh, Nanees F. El-Malkey, Shimaa Hadhod, Mohamed H. A. Gadelmawla, Sara Ali Kandeel, Amira F. A. Ahmed, Sahar M. El-Sayed
| Nature Verified
Abstract Obesity-induced cognitive decline has been linked to alterations in brain autophagy. However, research concerning the high-fat diet (HFD) impacts on the brain still lacks evidence, and results are controversial. Intermittent fasting (IF) may lead to increased neurogenesis levels in the hippocampus in neurodegenerative diseases; however, the involved molecular mechanisms are not well understood.
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