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Sarah Barakat on Muck Rack

Sarah Barakat

As seen in: Nature, Wiley Online Library, MDPI, ACS Publications
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Articles

Proteomic Data and Drug Implications for Cerebral Microvascular Endothelial Cells Under Varying Oxygen Levels - Scientific Data

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By Sarah Barakat, Hayriye Ecem Yelkenci, Kıvanç Kök
| Nature Verified
Abstract Hyperoxia in standard cell cultures (18 kPa O2) imposes cellular oxidative stress, potentially skewing research and drug screening outcomes. Cerebral microvascular endothelial cells (hCMEC/D3) experience no more than 7 kPa O2 in vivo. In this study, hCMEC/D3 cells were adapted to 5 kPa O2 for 5 days to optimize an in vitro physiological cell culture model. Using a SYNAPT G2-Si mass spectrometer, we compared the proteomic profiles of cells cultured under 5 kPa versus 18 kPa O2.
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Development of an Oxygen-Insensitive Nrf2 Reporter Reveals Redox Regulation under Physiological Normoxia

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By Seyed Mohammad Miri, Şeyma Nur Çimen, Sarah Barakat, Büşra N. Ata
| ACS Publications
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User Experience and Therapeutic Alliance of Treatment Completers of Clinician‐Supported Versus Self‐Help Online Intervention for Eating Disorders: A Mixed Methods Approach

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By Sarah Barakat, Phillip Aouad, Sean Rom, Marcellinus Kim
| Wiley Online Library Verified
A strong preference for human support was identified across all arms in the qualitative analyses, such that self-help participants described feeling deprived of clinician contact and clinician-supported participants reported clinician contact as a facilitator of adherence and motivation to engage with treatment.
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