Sarah Braner on Muck Rack

Sarah Braner

Verified
New York
As seen in: Chemical & Engineering News (C&EN), CNN, MSN, Business Insider, WJZ-TV (Baltimore, MD), Slate, The Daily Beast, ACS Publications, Flipboard, Business Insider Deutschland, ScienceAlert and
*checking twitter v intermittently!* life sciences @cenmag, prev @thisisinsider @slate @cnn. we don't need to talk about when i was at the messenger 🤪
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Articles

Designed GPCR minibinders access a particularly tough target

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By Sarah Braner 
| Chemical & Engineering News (C&EN)
About a third of all approved drugs target some kind of G protein–coupled receptor (GPCR). But designing drugs for these receptors poses difficulties because they sit in the cell membrane, and the binding pocket is heavily occluded. Many small molecules for these GCPRs have been identified from nature, but new work uses artificial intelligence design methods to formulate miniproteins that can target GCPRs (Nature 2026, DOI: 10.1038/s41586-026-10656-8).
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New AI-designed protein capsids go large for genetic medicine

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By Sarah Braner 
| Chemical & Engineering News (C&EN)
Genetic medicines, like those based on CRISPR/Cas9, need a delivery method to reach their intended destination. One popular vector to accomplish this is hollowed-out adeno-associated viruses. By repurposing a biological structure that’s evolved to enter cells, it’s possible to introduce genetic medicine instead of viral material. However, these viral vectors can’t hold a very big payload, being restricted to about 4.7 kilobases.
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2026 Talented 12: Euna Yoo

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By Sarah Braner 
| Chemical & Engineering News (C&EN)
Current affiliation: US National Cancer Institute Age:41 PhD alma mater: University of Kansas My favorite movie is: “Billy Elliot, a story about a boy growing up in a coal-mining town who discovers a love for ballet. I love the heartwarming and inspirational message about finding your place and breaking stereotypes.” My alternate-universe career is: “Bookstore owner. I find joy in looking at and touching paper books and indulging in stories.
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