Gallbladder cancer (GBC) is a rare, but lethal cancer with a median survival rate of >1 year [1]. Chile has one of the highest GBC incidences in the world with 5.6 per 100,000 [2]. GBC incidence and mortality in Chile is highest for women of Amerindian ancestry, particularly Mapuche women [1,3]. Gallbladder disease is the primary risk factor for GBC resulting in a chronic pro-inflammatory state [4].