Ad Director at The Santa Barbara Independent. media, travel, real estate, newspapers, SF Giants, baseball, fun, shiba inu, paleo, beach, sunshine, HHH
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Articles by Sarah Sinclair
The Home Page | Unlikely Heirlooms and Elephant Escapes
To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter Iconic Ikea Ideas | Photo Credit: Kaitlin Green I often find myself straddling the line between sticking to my budget and rewarding myself with a new little something for my home. Especially this time of year.
Medical Cannabis and Menopause: Evidence, Access and What Women are Asking
More women are exploring medical cannabis to manage symptoms such as sleep disturbances, anxiety, and chronic pain during the menopause. But while patient interest is growing, the science hasn’t caught up. What does the evidence actually tell us? And could cannabis-based medicines have a role alongside established treatments? Can medical cannabis help with menopause?
The Home Page | Pumpkins, Plot Twists, and Property Crushes
Pumpkin Party Pals | Photo Credit: Courtesy Spooky season is here! As you plan your costumes and decorations — creepy, cute, comical, or somewhere in between — don’t forget the most important part: your pumpkin! Karen, Erin, and Lyndsey of The Spechler and Beck Team are having a pumpkin party at Big Wave Dave’s pumpkin patch, 3865 State Street in La Cumbre Plaza, and you are invited! Saturday, October 17, from 11 a.m. to 1 p.m. No need to RSVP; just bring this ad on page 22 of this week’s...
The Endocannabinoid System, Explained: the Science Many Clinicians Were Never Taught
First discovered in the early 1990s, the endocannabinoid system (ECS) plays an important role in bodily function. Here, we unpack the science that is often missing from medical school curricula. What is the endocannabinoid system? The endocannabinoid system (ECS) is a signalling network found throughout the body. It uses naturally produced molecules called endocannabinoids, receptors including CB1 and CB2, and enzymes that make and break down those molecules.
Cannabis and Psychosis: Separating Risk from Rhetoric — What Clinicians Need to Know
The association between cannabis and psychosis is among the most studied — and most contested — areas of cannabinoid medicine. But the evidence points to a more nuanced picture than the debate often suggests. This article examines what clinicians need to know about THC, potency, individual vulnerability, and safe prescribing. Does cannabis increase the risk of psychosis?
The Home Page | Pups, Pianos, and Homes to Peruse
To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter 1124 Bath Street: front | Photo Credit: Sarah Sinclair As I’ve likely mentioned once, twice, or 3 million times, Scout and I cruise our downtown neighborhood daily, admiring gardens, getting to know neighbors, and keeping an eye on local housing happenings. One of the most charming homes on the market right now sits on our prime walking route at 1124 Bath Street.
Home Page: Tickled Pink & Seeing Green
To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter Pretty in Pink | Photo Credit: Alliance Sotheby’s Here’s a pink stucco home in Knoxville, Tennessee that stands out in a crowd. Built in 1929, and still boasting original touches throughout, I’m told that this home went under contract after just one day on the market.
Science edges towards breakthrough in male contraception
The review found differences in care for conditions including cardiovascular disease, kidney disease and Parkinson’s, with women less likely to receive some active treatments. Of 38 studies analysed, 33 found women were less likely than men to be offered active treatment.
Medical Cannabis for Anxiety in the UK: What the Evidence Actually Shows
Anxiety is one of the most common psychiatric conditions for which medical cannabis is prescribed in the UK, but the evidence base remains mixed. While some studies and real-world data report meaningful improvements, controlled trials remain limited and inconsistent. On the London agenda Managing risk and maximising benefit in mental health care London · 26 November 2026 Managing risk and benefit in mental-health care is a key session at the Cannabis Health Symposium.
How Much Does Medical Cannabis Cost in the UK? 2026 Price Guide
How much does medical cannabis cost? Medical cannabis costs can vary quite significantly in the UK depending on the provider, medication, prescribed dosage, and clinic fees. In 2026, medical cannabis flower costs an average of £6.67 per gram, while the average initial clinic consultation fee is around £50. Very few prescriptions are funded through the NHS.
NHS Medical Cannabis: Who Can Get It, How Pathways Work, and Why Access is Still Rare
Is medical cannabis prescribed on the NHS? Yes, medical cannabis can be prescribed on the NHS in the UK, but access is extremely limited. NHS prescriptions are largely restricted to licensed cannabis medicines for certain forms of epilepsy, multiple sclerosis and chemotherapy-induced nausea and vomiting.
The Home Page | A Little Cabin Fever
A Little Cabin in the Woods | Courtesy: Homes.com To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter I’m going off-grid next week! We’re heading up to explore King’s Canyon National Park and the surrounding wilderness. Big trees, lots of lakes, no laptops, and therefore … no newsletter next Sunday.
Professor David Nutt to Explore the Future of Medical Cannabis Research at London Symposium
Former chair of the Advisory Council for the Misuse of Drugs and founder of Drug Science, Professor David Nutt, is leading a line-up of esteemed speakers at the Cannabis Health Symposium in London later this year. The CPD-accredited Cannabis Health Symposium returns to London for a full day of evidence-led education across policy, regulation, access and clinical practice, bringing together healthcare professionals, industry and patient advocates.
The Home Page | So Santa Barbara
To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter Admiring El Andaluz | Photo Credit: Sarah Sinclair I got to visit one of my favorite buildings in Santa Barbara this week. El Andaluz, a seven-unit building at 531 Chapala Street is one of the most distinctive Jeff Shelton creations in Santa Barbara. I know, I know, distinctive + Shelton in the same sentence is redundant.
A Life Lived by the Tide
Address: 5325 Dorwin Lane Status: On the Market Price: $6,950,000 I knew Elijah was my person when I realized he plans his day around the tide. Not every day, mind you. He has a more-than-full-time career that demands his attention most of the time. But when he has free time, he knows the weather forecast, the phases of the moon, and the tide tables. He’s always ready for adventure, and his keen awareness of the natural world suits me just fine.
The Home Page | Dolly, Hubba Hubba, & a Home Among the Oaks
To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter Growing Solvang Tribute to Dolly | Photo Credit: Cris Lapp As the world mourns the loss of Dolly Parton this week, the legendary singer, songwriter and philanthropist’s Solvang connection is also receiving attention.
The Home Page | Treasure Hunts for Home Lovers
To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter Ever wanted to walk through the homes you admire in magazines? Dwell is giving us that opportunity with their annual “Dwell Open House: Los Angeles” event on October 17. Featuring three distinctive Eastside L.A. homes in a self-guided, three-hour tour, the event starts off at Frank Lloyd Wright’s Hollyhock House, the UNESCO World Heritage site shown above.
The Home Page | A Little More Summer, Please
To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter With school starting, Fiesta in the rearview mirror, and — egads! — the sun setting before 8 p.m., I’m reluctantly facing the reality that summer won’t last forever. We’ve still got plenty of sunshine left here in Santa Barbara, but if you need a little insurance against the coming darkness, take a look at these bathroom beauties from The Bold Bathroom Company.
The Home Page | Encore!
To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter As the final flamenco notes of Old Spanish Days Fiesta fade away, the homes around us are still putting on quite a show. Let’s take a tour of some nearby homes for sale worth celebrating. The home on our cover this week is one of those magical properties that never looks quite the same twice.
The Home Page | Fiesta, Fairytales & Front Porches
Fiesta 2024 | Credit: Courtesy To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter In Santa Barbara, August means Fiesta!! Each year, the Santa Barbara Association of Realtors celebrates the start of Fiesta week by throwing a great big open house at their office on Chapala Street.
The Home Page | Sunny Scenes and a Snowy Escape
To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter Is it just me, or does a cancelled meeting sometimes feel like a mini-vacation? When my standing 10 a.m. Friday meeting was called off, I immediately switched into open-house mode and pointed my car toward Hope Ranch. Cruising through the gates of this storied enclave on a sunny morning, it didn’t take long for work to feel very far away.
NHS Trust Approves UK-First Inpatient Medical Cannabis Policy
An NHS trust in Devon has become the first to approve a standard procedure for patients to continue taking their prescribed cannabis-based medications while in hospital. The policy, which aims to give medical cannabis patients a clear, safe pathway for administering these medicines when admitted to hospital, was approved by bosses at Devon Partnership NHS Trust (DPT) in May.
The Home Page | Palm Springs, Pups, & Perfect Spaces
To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter What makes a house feel like home? Sometimes it’s groundbreaking architecture. Sometimes it’s a thoughtful design. And sometimes it’s simply making room for the furry family members who think they own the place.
Chanelle McCoy Health Claims First Positive EFSA Opinion on CBD Novel Food Application
Chanelle McCoy Health says it has successfully passed through the European Food Safety Authority (EFSA)’s Novel Food application process, marking a potentially significant breakthrough after the regulator paused CBD assessments in 2022. The company confirmed that it has received a draft positive scientific opinion from EFSA on its Novel Food application (EFSA-Q-2020-00257), which would make it the first to clear the agency’s safety assessment.
The Home Page | Color Me Inspired
To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter One of my favorite blogs delivered this colorful Spanish Revival remodel to my inbox this week, and I instantly fell in love. The home is packed with charming details, but one room completely stole the show. The heart of every home is the kitchen, and this one has plenty of heart. Just look at the stove, the playful mix of tile patterns, and those leaded-glass cabinet doors.
The Home Page | Wallpaper Whimsy & Wildflower Views
To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter Happy July! Hitting the halfway point of the year always makes me pause and take stock of my goals and reminds me that it’s never too late to start that project that’s been on the list for way too long. At least, that’s what I told myself as I drove to Home Depot last night and bought a curtain rod for my still-bare kitchen window. My thinking?
Who Will Profit Most When the Drug War Ends?
The day I finish reading The Next Fix: The Winners and Losers Inside the Future of Drugs, by Professor Kojo Koram, a London-based legal scholar, I also see that a British cannabis clinic has been named eighth in the Sunday Times’ list of 100 fastest-growing private companies. In my five years of reporting on the global cannabis and psychedelic industries, I’ve seen this growth happen in real time, as the gap between those who can afford legal access and those who remain criminalized widens.
Why a Medical Cannabis Policy Should be Mandatory for Employers
First reported on Cannabis Health Thousands of people in the UK are legally prescribed cannabis-based medicines for chronic health conditions, and employment remains the single biggest reason they seek legal support, new data from Releaf’s legal helpline shows. For many patients, obtaining a medical cannabis prescription is only the beginning of the challenges they have to navigate.
The Home Page | Dad’s Day and Dream Homes
To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter Happy Father’s Day! Happy Summer Solstice! We’ve got a double dose of reasons to celebrate on this fine sunny Sunday. First up, we’ve got a home that’s ready to celebrate summer with a mini-orchard outside that includes apricot, plum, pomegranate, citrus, and fig trees, plus raised vegetable beds and plenty of room for dining al fresco.
The Cannabis Debate Is Not Just About Legalization Anymore, It’s About Who Benefits Original
Recreational cannabis is now legal in nearly half of U.S. states, with sales exceeding $30 billion last year (Photo by Spencer Platt/Getty Images) Getty Images Generations of activists have protested against cannabis prohibition, taking to the streets in cities around the world to lobby for legalization. But a major global review published this week, suggests this once-controversial conversation is no longer a question of whether cannabis should be regulated, but how— and what comes next.
The Cannabis Debate Is Not Just About Legalization Anymore, It’s About Who Benefits
8 hours ago States that have legalized recreational cannabis have collected more than $28 billion in tax revenue over the past roughly 12 years, according to a new report from the cannabis policy reform group Marijuana Policy Project. It all started when Colorado and Washington broke ground as the first states …
Like Father, Like Realtor: Keeping It All in the Family
Real estate comes with long hours, tight deadlines, plentiful personalities, and never-ending negotiations. Imagine navigating all of that with your dad — or your son — watching over your shoulder every step of the way. This Father’s Day, we asked three Santa Barbara father-son Realtor teams what it’s like to work side by side.
The Home Page | Abodes to Envy and Style for Right Meow
To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter This week’s issue of the Independent is our annual Pets & Animals edition, with stories on horse therapy, rascally raccoons, and plenty more. My sidekick, Scout, even makes a cameo appearance in our Indy pets roundup. This celebration of our furry companions got me thinking about a clever design idea that crossed my desk this week.
Ukraine Issues First Medical Cannabis Prescriptions, Two Years After Legalisation
First published on Cannabis Health On Thursday, 11 June, the first medical cannabis products were prescribed by neurologists at the Vinnytsia Regional Clinical Psychoneurological Hospital to Lyudmila Monastyrska, a patient with multiple sclerosis, and Yaroslav Yurchuk, a veteran who lost his leg a year ago while fighting in the Pokrovsk area.
Ukraine War Veteran and MS Patient Receive First Medical Cannabis Prescriptions
Two years on from the legalisation of medical cannabis in Ukraine, patients have received the first legal prescriptions for cannabis-based medicines. On Thursday, 11 June, the first medical cannabis products were prescribed by neurologists at the Vinnytsia Regional Clinical Psychoneurological Hospital to Lyudmila Monastyrska, a patient with multiple sclerosis, and Yaroslav Yurchuk, a veteran who lost his leg a year ago while fighting in the Pokrovsk area.
Cannabis-Based Drug Receives First European Market Approvals for Chronic Back Pain
After more than a decade in development, a full-spectrum cannabis extract has received market authorisation in Germany and Austria, with UK approval expected by the end of the year. Developed by German biopharmaceutical company Vertanical, Exilby® (also known as VER-01) will now be prescribed for the treatment of chronic lower back pain with a neuropathic component, and is expected to be eligible for reimbursement in line with national processes.
The Home Page | Sunny Spaces to chase the June Gloom
To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter Scout and I traverse the blocks in our downtown neighborhood enough that I feel like I “know” some of the houses pretty well. This four-unit complex at 308 West De la Guerra has always had a friendly facade with its plant-filled porch and welcoming yellow front doors.
Can Cannabis Help Close the Gender Health Gap? | Cannabis Europa 2026
Women are increasingly turning to medical cannabis to manage conditions ranging from endometriosis and chronic pain to menopause symptoms and sexual dysfunction. But while interest in alternative treatments like cannabis-based medicines continues to grow, so too does a broader conversation about why so many women feel conventional healthcare has failed to meet their needs in the first place.
Why Psychedelics Are Gaining Support Across The Political Spectrum Original
Bryan Hubbard, CEO of Americans for Ibogaine, spoke at an event in London this week, where he was interviewed by Labour MP Charlotte Nichols. Yuli Gates In the wake of a landmark Executive Order accelerating psychedelic research and access in the U.S., new polling suggests support for psilocybin-assisted therapy now extends across Britain’s political spectrum.
The Home Page | Desert Detours & a Redwood Retreat
To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter “Redwood sanctuary in the heart of Montecito” ?!? When the photos for this listing came across my desk, I genuinely thought it had to be in Big Sur. But nope, it’s right here in Montecito, tucked beside Hale Park.
The Home Page | Magic at the Mission and More
This edition of The Home Page was originally emailed to subscribers on May 24, 2026. To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter Credit: Sarah Sinclair Buying my house felt like a dream come true. And, in all honesty, it was a little terrifying, too.
The Home Page | Pearls of Wisdom & Mermaid Dreams
This edition of The Home Page was originally emailed to subscribers on May 17, 2026. To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter Give me a cute cottage over an ostentatious estate any day; $13,995,000 listings aren’t usually my cup of tea. However, this 8-bedroom, 10-bathroom estate behind private gates outside of Austin, Texas, caught my attention with two little words: Lazy. River.
Carboplatin with or without nivolumab in metastatic triple-negative breast cancer: a randomized phase II trial
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Abstract This multi-institutional randomized phase II clinical trial (NCT03414684) investigated the efficacy and safety of carboplatin plus nivolumab compared to carboplatin in metastatic triple-negative breast cancer (mTNBC). The primary endpoint was progression-free survival (PFS) in a modified intention-to-treat (mITT) population of patients with chemotherapy-naïve (i.e., first-line) mTNBC.
By Ana C. Garrido-Castro, Noah Graham, Katelyn X. Li, Jett Crowdis, Kevin Bi, Jihye Park, Ricardo Garcia Pastorello, Yvonne Y. Li, Hersh V. Gupta, Thomas Kuntz, Russell Petry, Lincoln W. Pasquina, Ashka Patel, Molly DiLullo, Anna Frey, Merrida A Childress, Robert Wesolowski, Natalie Sinclair, Sarah Sinclair, Steve Lo, Nadine Tung, Peter Kaufman, Caroline Block, Wendy S. Chen, Kai W. Wucherpfennig, Ye Tian, Amy Williams Verified, Satabhisa Mukhopadhyay, Tathagata Dasgupta, Stuart J. Schnitt, Andrew D. Cherniack, Jennifer A. Ligibel, Nancy Lin, Elizabeth A. Mittendorf, Nabihah Tayob, Eliezer Van Allen, Sara M. Tolaney, Lynn Bi, Paulina Lange, Victoria Attaya, Meredith Faggen, Jeanna Walsh, Madhavi Toke, Romualdo Barroso
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Nature
Verified
CQC Concerns Add to Scrutiny of UK’s Private Medical Cannabis Sector
The Care Quality Commission has raised several concerns about patient safety and prescribing practices at a private medical cannabis clinic, following an inspection last year that identified multiple regulatory breaches. In a report published in February, regulators found failures in safe care and treatment, governance and clinical oversight, warning that medicines were not always prescribed in line with current legislation or best practice.
The Home Page | Pink Gelato and Purple Trees
This edition of The Home Page was originally emailed to subscribers on May 10, 2026. To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter One of the local houses that I’ve admired over the years is The Pagoda House, which sits on the corner of East Valerio, between Prospect and Grand Avenues. I was lucky enough to visit ten years ago, and write about my love affair with the house.
Clearly A Crush on Clearview Road
Address: 1421 Clearview Road Status: On the market Price: $2,850,000 When it comes to house hunting, I’ll admit it — I fall fast. Give me wisteria twining its way up a balcony, the flicker of a wood-burning fireplace, or a perfectly arched doorway, and I’m swooning. Consider these details my Achilles’ heels, or perhaps my love language. So, it was hardly a surprise that the Spanish-style charmer at 1421 Clearview Road swept me off my feet.
The Home Page | Spring Cleaning, Botanic Birthday & Homes Galore
This edition of The Home Page was originally emailed to subscribers on May 3, 2026. To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter Botanic Garden’s Birthday Credit: Courtesy One of my favorite places to frolic is the Santa Barbara Botanic Garden. There are ever-changing flowers in bloom, trees to hug, and Scout is welcome, too! This year, “our garden” marks its centennial anniversary.
The Home Page | Pups, Pippin, Protea and Properties
This edition of The Home Page was originally emailed to subscribers on April 26, 2026. To receive Sarah Sinclair’s real estate newsletter in your inbox each Sunday, sign up at independent.com/newsletter I sure do love a behind-the-scenes tour, or a sneak-peek preview of something new. This week, I got both when I stopped by Pippin, the soon-to-be newest home design shop in downtown Santa Barbara.
Death of Medical Cannabis Patient Highlights Ongoing Stigma in Organ Transplant Programmes
The advocacy group Americans for Safe Access (ASA) has launched a new resource centre focused on organ transplantation and medical cannabis, following the death of patient Patrick Navarro, whose case has reignited concerns over discrimination in transplant eligibility.
Welsh Liberal Democrats Pass Motion Protecting Medical Cannabis Patients
The party voted overwhelmingly to approve the motion at its spring conference in Cardiff in March, marking what some have described as a critical step forward for cannabis patients’ rights in Wales. The motion was brought by Clwyd East and Flintshire Liberal Democrats, with Flintshire County Council becoming the first local authority to adopt the policy this month.
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