Sarah A. Chandler on Muck Rack

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Sarah A. Chandler’s Biography

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GB Payments is a UK based merchant service provider. Established since 2013, we’ve grown to help thousands of la businesses save money, grow and become smarter at taking payments.

Our focus is simple, we aim to support all UK businesses small or large to take payments for less whether you're in retail, a tradesmen, in hospitality or transportation.

We work with multiple UK and international merchant banks meaning we get more businesses approved faster.

We have a wide range of payment solutions …

Articles

Mechanism of degrader-targeted protein ubiquitinability

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By Charlotte Crowe, Mark A. Nakasone, Sarah A. Chandler, Michael H. Tatham
| biorxiv.org
Abstract Small molecule degraders of disease-driving proteins offer a clinically proven modality with enhanced therapeutic efficacy and the potential to tackle previously undrugged targets. Thermodynamically stable and kinetically long-lived degrader-mediated ternary complexes can drive faster, more profound and durable target degradation, however the mechanistic features by which they impact on target ubiquitination remain elusive.
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