Skip to main content
Saraï Mola on Muck Rack

Saraï Mola

As seen in: PLOS
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Saraï

Contact Saraï, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Prostaglandins and calprotectin are genetically and functionally linked to the Inflammatory Bowel Diseases

|
By Mohamad Karaky, Gabrielle Boucher, Saraï Mola, Sylvain Foisy
| PLOS
Fig 7. Proposed model of S100A8/9 induction. PTGIR and PTGER4 are activated by their ligands (PGI2 and PGE2 respectively) turning on the AC which converts ATP into cAMP; cAMP activates PKA which in turn triggers STAT3 by phosphorylation. STAT3 binds to the promoters (S9 Fig) of S100A8 and S100A9 inducing their expression. TLR4 and when activated by its ligand LPS, activates the JAK2-STAT3 pathway which induces the expression of S100A8/9 and inhibits NF-kB.
Open in Who Shared Issue with article?
See all 1 articles