Sarch C. Jenson on Muck Rack

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MARLOWE: Taxonomic Characterization of Unknown Samples for Forensics Using De Novo Peptide Identification

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By Fanny Chu, Anthony S Barente, Sarch C. Jenson, Dustin L. Crockett
| biorxiv.org
Abstract We present a computational tool, MARLOWE, for source organism characterization of unknown, forensic biological samples. The intent of MARLOWE is to address a gap in applying proteomics data analysis to forensic applications. MARLOWE produces a list of potential source organisms given confident peptide tags derived from de novo peptide sequencing and a statistical approach to assign peptides to organisms in a probabilistic manner, based on a broad sequence database.
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