Satoshi S. Nishizuka on Muck Rack

Satoshi S. Nishizuka

As seen in: Nature, Gastroenterology
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By Takeshi Iwaya, Satoshi S. Nishizuka
| Gastroenterology Verified
Article Info Publication History Accepted: March 18, 2021 Received: March 15, 2021 Publication stage In Press Journal Pre-Proof Footnotes Conflict of Interest: Dr. Iwaya received grant/research support from Nippon Kayaku, Chugai Pharmaceutical, and Daiichi Sankyo. Dr. Nishizuka received grant/research support form Array Jet, Taiho Pharmaceuticals, Boehringer-Ingelheim, Chugai Pharmaceutical, and Geninus. Dr. Nishizuka is an advisor/board member of CLEA Japan. Drs.
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Frequent post-operative monitoring of colorectal cancer using individualised ctDNA validated by multiregional molecular profiling

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By Takeshi Iwaya, Noriyuki Sasaki, Mizunori Yaegashi, Satoshi S. Nishizuka
| Nature Verified
Abstract Background Circulating tumour DNA (ctDNA) is known as a tumour-specific personalised biomarker, but the mutation-selection criteria from heterogeneous tumours remain a challenge. Methods We conducted multiregional sequencing of 42 specimens from 14 colorectal tumours of 12 patients, including two double-cancer cases, to identify mutational heterogeneity to develop personalised ctDNA assays using 175 plasma samples.
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