Satsuma Lab

Loading metrics Open Access Peer-reviewed Research Article ? This is an uncorrected proof. Citation: Zhou Y, Aslani S, Javanmardi Y, Brunet J, Stansby D, Carroll S, et al. (2026) Multiscale segmentation using hierarchical phase-contrast tomography and deep learning. PLoS Comput Biol 22(2): e1013923.

Keywords COVID-19 Hospitalisation Lung injury Biomarker Epithelial Evidence before this study Some survivors of acute COVID-19 infection have long-term symptoms that could suggest ongoing lung impairment. Searches performed in MEDLINE and Embase for SARS-COV-2 studies with radiological lung follow-up estimated that 50% of participants had inflammatory patterns and 29% had fibrotic patterns at a median of 3 months post infection.

We used pseudonymised patient-level, electronic health care records from the Clinical Practice Research Datalink (CPRD) GOLD database (January 2019). A detailed description of this resource is described elsewhere [26]. The study was approved by the MHRA (UK) Independent Scientific Advisory Committee [18_291], under Sect. 251 (NHS Social Care Act 2006). We established a cohort of IPF patients diagnosed between 1st January 1997 and 1st January 2019 from the patients with multiple registrations cohort.