Sayad Doobary

Olefins are a vital class of compounds that are frequently used as building blocks in synthesis, as well as in a variety of other applications in the pharmaceutical and materials industries.[1-4] Heteroatom-substituted alkenes are versatile functionalities in downfield applications,[5-7] and incorporation of a second heteroatom to give 1,2-di(hetero)alkenes enables a variety of derivatization pathways.

Sustainable and scalable one-pot synthesis of diaryliodonium salts Two one-pot routes from iodoarenes to diaryliodonium triflates have been developed in the sustainable solvent ethyl acetate. The first method yields the recently reported aryl(dimethylisoxazolyl)iodonium triflates, circumventing the need for stepwise synthesis of this chemoselective arylating reagent.

Hypervalent iodine chemistry with a mechanochemical twist The combination of mechanochemistry and hypervalent iodine chemistry has rarely been reported, despite the numerous advantages offered by this enabling technology. With this in mind, this study addresses the key issue of transforming hypervalent iodine-mediated, solution-based reactions into the mechanochemical realm, accompanied by benchmarking and sustainability studies of the different types of reactions.