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Sayantap Datta

As seen in: MDPI, Texas Medical Center
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Articles

Targeting the MYCN-MDM2 Pathways for Cancer Therapy: Are They Druggable?

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By Wei Wang, Yi Du, Sayantap Datta, Josef F. Fowler
| Texas Medical Center
Keywords MDM2, MYCN, Neuroblastoma, Signaling pathway, Targeted therapy Abstract Targeting oncogenes and their interactive partners is an effective approach to developing novel targeted therapies for cancer and other chronic diseases. We and others have long suggested the MDM2 oncogene being an excellent target for cancer therapy, based on its p53-dependent and -independent oncogenic activities in a variety of cancers.
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Acid Sphingomyelinase and Ceramide Signaling Pathway Mediates Nicotine-Induced NLRP3 Inflammasome Activation and Podocyte Injury

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By Mohammad Atiqur Rahman, Sayantap Datta, Saisudha Koka, Harini Lakkakula
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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High Mobility Group Box 1 (HMGB1): Molecular Signaling and Potential Therapeutic Strategies

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By Sayantap Datta, Mohammad Atiqur Rahman, Saisudha Koka, Krishna M. Boini
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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