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Sean Tierney on Muck Rack

Sean Tierney

As seen in: Medium, The Athletic, Nature, South China Morning Post, Bleacher Report, The Lancet, The Hockey Writers, CEOWORLD Magazine, The Pitt News, Scotsman Guide and
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Articles

LICHEN enables light-chain immunoglobulin sequence generation conditioned on the heavy chain and experimental needs - Communications Biology

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By Henriette Capel, Isaac Ellmen, Chris Murray, Giulia Mignone, Megan Black, Brendan Clarke, Conor Breen, Sean Tierney, Patrick Dougan, Richard Buick, Alexander Greenshields-Watson, Charlotte M. Deane
| Nature Verified
Abstract In developing therapeutic antibodies, the heavy chain is often prioritised due to its higher variability and its central role in antigen binding. An appropriate pairing of the light sequence is however important for antibody function. Here we present LICHEN, a heavy chain conditioned light sequence generation tool that enables collaborative light sequence design by leveraging computational capabilities alongside experimental expertise.
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Breaking bones and being set on fire

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By Sean Tierney
| The Hong Konger Verified
Director Yuen Woo-ping’s Iron Monkey (1993) was released at the tail end of the early 1990s resurgence of martial arts films spurred by the success of Tsui Hark’s Once Upon a Time in China series. That franchise starred Jet Li as Wong Fei-hung, the Chinese folk hero from Guangdong. Wong has been portrayed at different times by Kwan Tak-hing, Gordon Liu Chia-hui, Jackie Chan, Sammo Hung Kam-bo, and Vincent Zhao Wenzhuo, among others.
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Betting big on Hong Kong films

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By Sean Tierney
| The Hong Konger Verified
Hong Kong’s film industry has the ability to represent the city in all its (sometimes-sordid) glory. Thus, in a place that loves gambling, films about gambling are inevitable. Some of the earliest gambling films are blessed with such attention-grabbing titles as Gambling and Drinking/賭與酒 (1952) or The Gambler Who Pawns His Wife/ 爛賭二當老婆 (1964).
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