Skip to main content
Sebastian M. Shimeld on Muck Rack

Sebastian M. Shimeld

As seen in: Nature, Wiley Online Library, BioRxiv
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Sebastian M.

Contact Sebastian M., search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Whole-genome duplication shaped cell-type evolution in the vertebrate brain

|
By Yuanzhen Zhu, Shuai Zhang, Jiankai Wei, Huimin Liu, Chenggang Shi, Rongrong Pan, Yuwei Chen, Yan Xu, Qiye Li, Günter Wagner, Peter Holland, Guang Li, Sebastian M. Shimeld, Diego Dolgetta-Garcia, Katia Jindrich
| Nature Verified
Abstract The complex brains of vertebrates have more cell types than those of their closest relatives. Whole-genome duplications (WGDs) occurred during early vertebrate evolution1, but it is unclear whether the duplicated genes (ohnologues) facilitated cell-type evolution.
Open in Who Shared Issue with article?

Long-Read Sequencing Reveals Increased Isoform Diversity in Key Transcription Factor Effectors of Intercellular Signalling at the Invertebrate-Vertebrate Transition

|
By Nuria P. Torres-Aguila, Marika Salonna, Sebastian M. Shimeld, Stefan P Hoppler
| BioRxiv
Abstract Several intercellular signalling pathways (namely wingless - Wnt, Hedgehog - Hh, and Bone Morphogenetic Protein - BMP) are used repeatedly in animals throughout development and evolution, and are also frequent targets for disease-associated disruptions.
Open in Who Shared Issue with article?

Evolutionary origin of the chordate nervous system revealed by amphioxus developmental trajectories - Nature Ecology & Evolution

|
By Yichen Dai, Pingfen Zhu, Sebastian M. Shimeld, Xuming Zhou
| Nature Verified
Abstract The common ancestor of all vertebrates had a highly sophisticated nervous system, but questions remain about the evolution of vertebrate neural cell types. The amphioxus, a chordate that diverged before the origin of vertebrates, can inform vertebrate evolution. Here we develop and analyse a single-cell RNA-sequencing dataset from seven amphioxus embryo stages to understand chordate cell type evolution and to study vertebrate neural cell type origins.
Open in Who Shared Issue with article?
See all 5 articles