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Sebastian Major on Muck Rack

Sebastian Major

Canada
As seen in: BioRxiv, EBioMedicine
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Articles

Blood-brain barrier opening as a predictor of epilepsy and mortality after subarachnoid haemorrhage

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By Jens P. Dreier, Humboldt-Universität zu Berlin, Sebastian Major, Robert Koch-Institute
| EBioMedicine Verified
Keywords Blood–brain barrier Epilepsy Spreading depolarisation Electrographic seizure Subarachnoid haemorrhage Neurodegeneration Evidence before this study We searched PubMed for articles published in any language addressing the possible association between blood–brain barrier (BBB) damage in patients with subarachnoid haemorrhage (SAH) or in animals subjected to experimental SAH and the risk of developing late-onset epilepsy or death.
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Prediction of Stroke Outcome in Mice Based on Non-Invasive MRI and Behavioral Testing

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By Stefan Koch, Sebastian Major, Tracy Farr, Felix Knab
| BioRxiv
New Results doi: https://doi.org/10.1101/2022.05.13.491869 Abstract Background: Prediction of post-stroke outcome using the degree of subacute deficit or magnetic resonance imaging is well studied in humans. While mice are frequently used animals in preclinical stroke research, systematic analysis of outcome predictors is lacking. Methods: We introduced heterogeneity into our study to broaden the applicability of our prediction tools.
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