Sebastián Real

As a developer, I’ve tried countless tools over the years, but some apps have earned a permanent spot in my daily workflow. These aren’t just applications I use — they’re the digital tools that make coding more enjoyable, efficient, and could I say, fun. Here’s my curated list of go-to apps that I couldn’t imagine coding without. Regular expressions can be intimidating, even for seasoned developers. That’s where Expressions becomes invaluable.

Abstract Cell communication within the tumor microenvironment (TME) plays a pivotal role in cancer progression, yet little is known about whether this communication differs between anatomically paired organs. Here, we report that breast tumors arising in the left (L) versus right (R) mammary glands exhibit significant asymmetry in composition, bioelectric state, and epigenetic regulation suggesting the existence of a stable, lateralized tumor TME shaped by differential cell communication.

Abstract Basal-like breast cancer (BLBC) is characterized by an aggressive clinical course, high genomic instability, and limited therapeutic options. The Inhibitor of Differentiation 4 (ID4) protein has been identified as a critical regulator of BLBC, where its overexpression correlates with poor prognosis. However, the mechanistic contributions of ID4 to BLBC tumorigenesis remain incompletely understood.