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Sebastiano Barco

As seen in: Wiley Online Library, Frontiers, MDPI
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Articles

Accidental cannabis intoxication in two young children: clinical presentation and toxicokinetics - a case series

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By Alessia Cafaro, Federica Pigliasco, Sebastiano Barco, Emanuela Piccotti, Roberto Bandettini, Francesca Mattioli, Giuliana Cangemi, Ilaria Negro, Luca Manfredini, Samir Mahameed, Carla Debbia
| Frontiers
CASE REPORT article Volume 16 - 2025 | https://doi.org/10.3389/fphar.2025.1695194 Introduction The escalating accidental exposure of children to edible Cannabis (Cannabaceae family) products and passive smoke is becoming a significant concern (Richards et al., 2017; Vo et al., 2018).
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A Novel LC-MS/MS Method for the Measurement of Elexacaftor, Tezacaftor and Ivacaftor in Plasma, Dried Plasma Spot (DPS) and Whole Blood in Volumetric Absorptive Microsampling (VAMS) Devices

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By Federica Pigliasco, Alessia Cafaro, Sebastiano Barco, Federico Cresta
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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A VAMS‐based LC-MS/MS method for precise cenobamate quantification in epilepsy (patients)

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By Federica Pigliasco, Alessia Cafaro, Sebastiano Barco, Margherita Biondi
| Wiley Online Library Verified
Cenobamate (CNB) is an antiepileptic drug and used for treatment of focal-onset seizures in adult patients (≥18 age). The method is based on a rapid organic extraction from VAMS and separation on a reversed-phase C-18 UHPLC column after addition of deuterated internal standards. Our method is suitable for TDM, and this study suggests that VAMS allows monitoring of CNB concentration.
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