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Sejoon Choi on Muck Rack

Sejoon Choi

As seen in: BioRxiv
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Articles

Regulation of dopamine release by tonic activity patterns in the striatal brain slice

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By Nezha Bouhaddou, Siham Boumhaouad, Emily A Makowicz, Sejoon Choi
| BioRxiv
Abstract Voluntary movement, motivation, and reinforcement learning depend on the activity of ventral midbrain neurons that extend axons to release dopamine (DA) in the striatum. These neurons exhibit two patterns of action potential activity: a low-frequency tonic activity that is intrinsically generated, and superimposed high-frequency phasic bursts that are driven by synaptic inputs.
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