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Şeniz Erdem on Muck Rack

Şeniz Erdem

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Articles

Exploring microbial-derived chondroitin sulfate as a suppressor of microglial inflammation and pyroptosis

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By Önder Otlu, Mehmet Erdem, Ayse Sebnem Erenler, Şeniz Erdem, Ahmet Alver
| Nature Verified
Abstract Neuroinflammation is a protective immune response in the central nervous system (CNS), primarily regulated by glial cells such as microglia, astrocytes, and oligodendrocytes. Microglia serve as the main innate immune cells, initiating responses to pathological stimuli through mechanisms including inflammasome activation. The NLRP3 inflammasome plays a central role in promoting inflammation and pyroptosis.
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