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Serkan Sayin on Muck Rack

Serkan Sayin

As seen in: PLOS Biology, BioRxiv, eLife
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Articles

Bacterial population dynamics during colonization of solid tumors

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By Serkan Sayin, Motasem ElGamel, Brittany Rosener, Michael A Brehm
| BioRxiv
Abstract Bacterial colonization of cancer tumors is widespread. While the clinical significance of intratumor bacteria is widely investigated, the dynamics of tumor colonization remain underexplored. We monitored bacterial population dynamics in murine tumors after introducing genetically barcoded Escherichia coli cells by intravenous or intratumor injections.
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Machine Learning: Finding the right type of cell

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By Valentyna Zinchenko, Flora Mikaeloff, Serkan Sayin, Louis K Scheffer
| eLife
Since the advent of microscopy in the 17th century, it has become well established that organisms are divided into tissues made up of different types of cells, with cells of the same type typically performing the same role. This simplifies the task of understanding a biological system immensely, as there are many fewer cell types than individual cells (Masland, 2001).
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Generative power of a protein language model trained on multiple sequence alignments

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By Damiano Sgarbossa, Umberto Lupo, Anne-Florence Bitbol, Serkan Sayin
| eLife
Accepted manuscript, PDF only. Full online edition to follow. Share this article Cite this article Generative power of a protein language model trained on multiple sequence alignments eLife 12:e79854. https://doi.org/10.7554/eLife.79854 Abstract Computational models starting from large ensembles of evolutionarily related protein sequences capture a representation of protein families and learn constraints associated to protein structure and function.
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