Seryoung Park on Muck Rack

Seryoung Park

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Articles

Dual-mode action of scalable, high-quality engineered stem cell-derived SIRPα-extracellular vesicles for treating acute liver failure - Nature Communications

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By Seohyun C. Kim, Yoon Kyoung Kim, Seonghyun Kim, Yong-Soon Choi, Inkyu Lee, Yoonjeong Choi, Jiwan Woo, Jeongbin Park, Seung-Yoon Park, Gi Beom Kim, Gi-Hoon Nam, Seryoung Park, Min Kyoung Jo
| Nature Verified
Abstract Acute liver failure (ALF) is a life-threatening condition caused by rapid hepatocyte death and impaired liver regeneration. Here we show that extracellular vesicles engineered to express Signal Regulatory Protein Alpha (SIRP-EVs), produced via a scalable 3D bioreactor process with high yield and purity, exhibit significant therapeutic potential by targeting damaged cells and promoting tissue repair.
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