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Seth Weinberg on Muck Rack

Seth Weinberg

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Articles

Electrodiffusion in cardiac intercalated disc nanostructures alters cell-cell action potential transmission via ephaptic coupling: A model study

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By Ena Ivanovic, Marina Vannucci, Nicolae Moise, Seth Weinberg
| Wiley Online Library Verified
Introduction During every heartbeat, the contraction of cardiomyocytes is triggered by electrophysiological signals propagating through the heart, called action potentials (APs). Disturbances of AP propagation can lead to life-threatening arrhythmias (Empana et al., 2022; Lip et al., 2016; Surawicz, 1985).
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The influence of intercalated disk nanostructure on local ionic currents and cardiac conduction

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By Davis Heart, Seth Weinberg
| buff.ly
Significance Cardiac conduction critically depends on the nanoscale organization of the cell-cell junction, the intercalated disk (ID). We employed a refined 3D finite element mesh model of the ID nanostructure, integrating key ion channels and gap junctions and their nonuniform distributions, thus facilitating the quantification of the relative role of these properties on cardiac conduction.
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Distinguishing syndromic and nonsyndromic cleft palate through analysis of protein-altering de novo variants in 818 trios

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By Kelsey Robinson, Sarah Curtis, Justin E. Paschall, Wasiu Lanre Adeyemo, Terri H Beaty, Azeez Butali, David Cutler, Michael Epstein, Jacqueline T. Hecht, Gary Shaw, Lina Uribe, Jeffrey C. Murray, Harrison A. Brand, Seth Weinberg, Mary L. Marazita, Kimberly Doheny, Elizabeth J. Leslie-Clarkson, Carmen J. Buxó, J.J. Gowans
| The American Journal of Human Genetics Verified
Keywords cleft palate variation phenotypic heterogeneity genetic architecture de novo Get full text access Log in, subscribe or purchase for full access. References 1. Mai, C.T. ∙ Isenburg, J.L. ∙ Canfield, M.A. ... National population-based estimates for major birth defects, 2010-2014 Birth Defects Res. 2019; 111:1420-1435 2. Stewart, J.M. ∙ Ott, J.E. ∙ Lagace, R. Submucous cleft palate: prevalence in a school population Cleft Palate J. 1972; 9:246-250 3. Kang, S.L. ∙ Narayanan, C.S. ∙ Kelsall, W.
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