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Seulhee Kim

As seen in: MDPI, BioRxiv
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Articles

An Innovative Mitochondrial-targeted Gene Therapy for Cancer Treatment

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By Kai Chen, Patrick Ernst, Seulhee Kim, Yingnan Si
| BioRxiv
Abstract Targeting cancer cell mitochondria holds great promise for cancer treatment, yet current strategies for specifically and effectively destroying cancer mitochondria in vivo are limited. Here, we introduce mLumiOpto, an innovative mitochondrial-targeted luminoptogenetics technology designed to directly disrupt the inner mitochondrial membrane (IMM) potential and induce cancer cell death.
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A CD276-Targeted Antibody-Drug Conjugate to Treat Non-Small Lung Cancer (NSCLC)

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By Kai Chen, Irene Cho, Jiashuai Zhang, Seulhee Kim
| MDPI
2. Materials and Methods 2.1. Ethics Statement The animal studies were conducted according to the Institutional Animal Care and Use Committee (IACUC) Protocol 2022A00000071, which was approved by the Institutional Biosafety Committee of Ohio State University (OSU).
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