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Seungmi Kim

As seen in: Nature, Memory Studies, BioRxiv
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Articles by Seungmi Kim

Structural transition of the immature poxvirus scaffold from preassembly to the scaffold lattice

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By Seungmi Kim, Seu-Na Lee, Bumhan Ryu, Hyeongseop Jeong, Eun Sung Kang, Jae Hoon Sul, Yong Kim, Dong-Gyu Jo, Jaekyung Hyun, Yeontae Jang, Hayeon Bae
| Nature Verified
Abstract During poxvirus morphogenesis, the external scaffold defines the shape and size of immature virions. However, its structural characterization has been hindered by the pleomorphic nature of authentic virus particles. Here, we present single-particle cryo-electron microscopy and cryo-electron tomography structures of two distinct in vitro assemblies of the vaccinia virus scaffold protein D13 that recapitulate oligomeric states previously observed in situ.
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Rab11 suppresses neuronal stress signaling by localizing Dual leucine zipper kinase to axon terminals for protein turnover.

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By Seungmi Kim, Yaw Quagraine, Monika Singh, Jung Hwan Kim
| BioRxiv
Abstract Dual Leucine Zipper Kinase (DLK) mediates multiple neuronal stress responses, and its expression levels are constantly suppressed to prevent excessive stress signaling. We found that Wallenda (Wnd), the Drosophila ortholog of DLK, is highly enriched in the axon terminals of Drosophila sensory neurons in vivo and that this subcellular localization is necessary for Highwire-mediated Wnd protein turnover under normal conditions.
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The axonal localization of Dual Leucine Zipper Kinase defines its protein-turnover

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By Seungmi Kim, Monika Singh, Jung Hwan Kim, Yaw Quagraine
| BioRxiv
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Longitudinal follow-up of serum biomarkers in patients with neuromyelitis optica spectrum disorder

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By Hyunjin Kim, Eun-Jae Lee, Seungmi Kim, Lyn-Kyung Choi
| SAGE Publishing
1. Papadopoulos, MC, Verkman, AS. Aquaporin 4 and neuromyelitis optica. Lancet Neurol 2012; 11: 535–544. Google Scholar | Crossref | Medline | ISI 2. Lee, EJ, Lim, YM, Kim, SY, et al. The clinical and prognostic value of antinuclear antibodies in NMO-IgG seropositive neuromyelitis optica spectrum disorder. J Neuroimmunol 2019; 328: 1–4. Google Scholar | Crossref | Medline 3. Fujihara, K. Neuromyelitis optica spectrum disorders: Still evolving and broadening. Curr Opin Neurol 2019; 32(3): 385–394.
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