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Sevana Khaloian on Muck Rack

Sevana Khaloian

As seen in: Gut Journal, BioRxiv
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Articles

Susceptibility to inflammatory bowel diseases promotes invasive carcinomas in a murine model of ATF6-driven colon cancer

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By Janine Kövilein, Adam Sorbie, Sevana Khaloian, Vanessa Küntzel
| BioRxiv
Abstract Chronic inflammation in inflammatory bowel disease (IBD) patients represents a risk factor for developing colitis-associated cancer (CAC). We previously linked the endoplasmic reticulum unfolded protein response (UPRER) signal transducer activating transcription factor 6 (ATF6) with spontaneous microbiota-dependent colonic adenoma development in mice expressing epithelial-specific activated ATF6 (nATF6IEC).
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Mitochondrial impairment drives intestinal stem cell transition into dysfunctional Paneth cells predicting Crohn’s disease recurrence

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By Sevana Khaloian, Eva Rath, Nassim Hammoudi, Elisabeth Gleisinger
| Gut Journal Verified
Inflammatory bowel disease Mitochondrial impairment drives intestinal stem cell transition into dysfunctional Paneth cells predicting Crohn’s disease recurrence Sevana Khaloian1, http://orcid.org/0000-0003-1910-1162Eva Rath1, Nassim Hammoudi2, Elisabeth Gleisinger1, Andreas Blutke3, Pieter Giesbertz4, Emanuel Berger1, Amira Metwaly1, Nadine Waldschmitt1, http://orcid.org/0000-0002-2012-7522Matthieu Allez2, http://orcid.org/0000-0002-6977-4085Dirk Haller1,5 1 Chair of Nutrition and Immunology,...
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Mitochondrial impairment drives intestinal stem cell transition into dysfunctional Paneth cells predicting Crohn’s disease recurrence

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By Technische Universität München, Eva Rath, Nassim Hammoudi, Sevana Khaloian
| Gut Journal Verified
Inflammatory bowel disease Mitochondrial impairment drives intestinal stem cell transition into dysfunctional Paneth cells predicting Crohn’s disease recurrence Sevana Khaloian1, http://orcid.org/0000-0003-1910-1162Eva Rath1, Nassim Hammoudi2, Elisabeth Gleisinger1, Andreas Blutke3, Pieter Giesbertz4, Emanuel Berger1, Amira Metwaly1, Nadine Waldschmitt1, http://orcid.org/0000-0002-2012-7522Matthieu Allez2, Dirk Haller1,5 1Chair of Nutrition and Immunology, Technische Universität München,...
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