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Seyhmus Bayar on Muck Rack

Seyhmus Bayar

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Articles

Kupffer cell programming by maternal obesity triggers fatty liver disease - Nature

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By Hao Huang, Lea Seep, Maria Viola, Eliana Franco Taveras, Nikola Makdissi, Jelena Zurkovic, Amir H Kayvanjoo, Klaus Wunderling, Malin Jessen, Lukas Kenner, Thomas Ulas, Stephan Grein, Charlotte Scott, Zhaoyuan Liu, Florent Ginhoux, Marc Beyer, Christoph Thiele, Felix Meissner, Dagmar Wachten, Kerim Acil, Diana Fink, Seyhmus Bayar, Katharina Mauel, Carolin Radwaniak
| Nature Verified
Abstract Kupffer cells (KCs) are tissue-resident macrophages that colonize the liver early during embryogenesis1. Upon liver colonization, KCs rapidly acquire a tissue-specific transcriptional signature, mature alongside the developing liver and adapt to its functions1,2,3.
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