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Seylan Ayan on Muck Rack

Seylan Ayan

As seen in: Nature, Royal Society of Chemistry
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Articles

A chloromethyl-triazole fluorescent chemosensor for O6-methylguanine DNA methyltransferase

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By Seylan Ayan, Adrian M. Rotaru, Esther G. Kaye, Gabrielle Juneau
| Royal Society of Chemistry Verified
A chloromethyl-triazole fluorescent chemosensor for O6-methylguanine DNA methyltransferase† Fluorescent chemosensors offer a direct means of measuring enzyme activity for cancer diagnosis, predicting drug resistance, and aiding in the discovery of new anticancer drugs. O6-methylguanine DNA methyltransferase (MGMT) is a predictor of resistance towards anticancer alkylating agents such as temozolomide.
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Proof-of-principle for two-stage photodynamic therapy: hypoxia triggered release of singlet oxygen

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By Seylan Ayan, Gurcan Gunaydin, Nisa Yesilgul-Mehmetcik, M. Emre Gedik
| Royal Society of Chemistry Verified
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Molecular demultiplexer as a terminator automaton

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By Engin U. Akkaya, Ilke S. Turan, Gurcan Gunaydin, Seylan Ayan
| Nature Verified
More than two decades after the seminal work by de Silva et al.1, molecule-based logic gates have reached a level of considerable sophistication2,3,4. Many examples of basic Boolean logic gates and various implementations of both combinatorial and sequential logic were reported5,6,7,8,9,10.
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