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Seyma Cengiz-Emek on Muck Rack

Seyma Cengiz-Emek

As seen in: PLOS Biology, BioRxiv
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Articles

CCDC66 regulation of cytoskeleton and cilia stability is important for signaling and epithelial organization

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By Jovana Deretic, Seyma Cengiz-Emek, Ece Seyrek, Elif Nur Firat-Karalar
| PLOS Biology Verified
Loading metrics Open Access Peer-reviewed Research Article ? This is an uncorrected proof. Citation: Deretic J, Cengiz-Emek S, Seyrek E, Firat-Karalar EN (2025) CCDC66 regulation of cytoskeleton and cilia stability is important for signaling and epithelial organization. PLoS Biol 23(7): e3003313. https://doi.org/10.1371/journal.pbio.3003313 Academic Editor: Renata Basto, Institut Curie, FRANCE Received: May 22, 2024; Accepted: July 11, 2025; Published: July 29, 2025 Copyright: © 2025 Deretic et al.
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Ccdc66 regulates primary cilium stability, disassembly and signaling important for epithelial organization

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By Jovana Deretic, Elif Nur Firat-Karalar, Seyma Cengiz-Emek, Ece Seyrek
| BioRxiv
Abstract The primary cilium is a conserved, microtubule-based organelle that transduces signaling pathways essential for development and homeostasis. It is a dynamic structure that assembles and disassembles in response to intrinsic and extrinsic stimuli while maintaining remarkable stability and tightly controlled length. Although cilium assembly is well-understood, less is known about the molecular players and pathways governing their stability, length and disassembly.
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