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Anticancer Structure-Activity Relationship in Well-Characterized Pt(IV) Compounds: Pt(CH 3 ) 2 I 2 {6,6’-dimethyl-2,2’-bipyridine} Cytotoxicity Against Colon and Ovarian Carcinoma Cell Lines

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By William Howard, Kraig A. Wheeler, Shadrach Stitz
| preprints.org
You are already at the latest version Well-defined, small-molecule, platinum-centered coordination compounds are of continued interest in both basic and applied research, particularly in medicinal chemistry and pharmaceuticals (i.e., cisplatin). Organoplatinum(IV) complexes have been reported to exhibit substantial in vitro cytotoxicity across a range of cancer cell lines.
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