Shafee Syed-Quadri on Muck Rack

Shafee Syed-Quadri

As seen in: Frontiers
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Heterogeneous DNA methylation and gene expression patterns underly metabolic plasticity in canine astrocytoma-derived stem-like cells

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By Ryan G. Toedebusch, Chang-Il Hwang, Orwa Aboud, Kevin Woolard, Daniel York, Maciej Parys, Peter J. Dickinson, Frederick J. Meyers, John McPherson, Christine Toedebusch, Shafee Syed-Quadri
| Frontiers
1 Introduction The concept of cancer stem cells originated in 1937 when a mouse injected with a single leukemia cell developed a rapidly lethal leukemia (1). Over the past several decades of research, cancer stem cells are now defined as a subpopulation of tumor cells that have characteristics of sustained self-renewal, persistent proliferation, and tumor initiation. Stem cells have been identified in several cancers, including high-grade glioma (HGG) (2, 3).
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