SHAHID HABIB

Background: Acute-on-chronic liver failure (ACLF) is characterized by acute deterioration in chronic liver disease (CLD), leading to organ failures. Alcohol is a major cause and trigger of ACLF, particularly in alcoholic liver disease (ALD). However, the impact of acute alcohol consumption in patients with non-alcoholic CLD (CLD-Others) is less well understood.

Introduction Naegleria fowleri, also recognized as the “brain-eating amoeba”, is a eukaryotic, highly pathogenic, and free-living amoeba. Natural habitats for N. fowleri include soil and freshwater, and warm water temperatures are assumed to contribute to its occurrence. It belongs to the phylum Percolozoa, class Heterolobosea, and is the etiological agent of Primary Amoebic Meningoencephalitis (PAM) (1, 2).