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Identification of a Distal Locus Enhancer Element That Controls Cell Type-Specific TNF and LTA Gene Expression in Human T Cells
Open Access Luke D. Jasenosky, Aya Nambu, Alla V. Tsytsykova, Shahin Ranjbar, Viraga Haridas, Laurens Kruidenier, David F. Tough and Anne E. Goldfeld J Immunol November 1, 2020, 205 (9) 2479-2488; DOI: https://doi.org/10.4049/jimmunol.1901311 Key Points Epigenetic changes predict cell type–specific TNF/LT locus gene expression. Distal element hHS-8 regulates TNF and LTA gene expression in activated T cells.
Identification of a Distal Locus Enhancer Element That Controls Cell Type-Specific TNF and LTA Gene Expression in Human T Cells
Open Access Luke D. Jasenosky, Aya Nambu, Alla V. Tsytsykova, Shahin Ranjbar, Viraga Haridas, Laurens Kruidenier, David F. Tough and Anne E. Goldfeld J Immunol September 25, 2020, ji1901311; DOI: https://doi.org/10.4049/jimmunol.1901311 Key Points Epigenetic changes predict cell type–specific TNF/LT locus gene expression. Distal element hHS-8 regulates TNF and LTA gene expression in activated T cells. Abstract The human TNF/LT locus genes TNF, LTA, and LTB are expressed in a cell type–specific manner.
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