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COVID-19 disruptions and spring surges: an interrupted time-series analysis of tuberculosis diagnostic challenges in Northeast Iran
Abstract Tuberculosis (TB) remains a significant public health challenge in Northeast Iran, yet longitudinal data evaluating regional transmission patterns following COVID-19 disruptions remain limited. This cross-sectional study, conducted from 2017 to 2023 at Qaem University Hospital, Mashhad, Iran, analyzed 14,572 patients with suspected TB using smear microscopy, culture, and PCR to characterize the test positivity rate (TPR), temporal shifts, and diagnostic challenges.
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