Shamba Chatterjee on Muck Rack

Shamba Chatterjee

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Articles

Cannabidiphorol (CBDP) acts as a negative allosteric modulator at two distinct sites of cannabinoid receptor 1

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By Pankaj Pandey, Ayat Zagzoog, Ikhlas A. Khan, Jason Paris, Robert B. Laprairie, Amar G. Chittiboyina, Theodor Zaharia, Shamba Chatterjee
| Nature Verified
Abstract While Δ9-tetrahydrocannabinol (THC) offers significant pain relief, its psychoactive side effects limit its clinical utility. The discovery of cannabidiol (CBD) as a negative allosteric modulator (NAM) of cannabinoid receptor 1 (CB1R) establishes allosteric targeting as a viable framework for refining cannabinoid-based therapeutics.
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