Shaoxiong Huang

Abstract Fibrosis is a severe pathological outcome of many chronic diseases, yet the therapeutic potential of targeting the altered major histocompatibility complex (MHC) class I immunopeptidome remains largely unexplored. Here we characterized the MHC class I immunopeptidomes from both fibrotic foci of human idiopathic pulmonary fibrosis lung explants and bleomycin-treated mice, identifying a diverse repertoire of fibrosis-associated peptides.

1Department of Gastrointestinal Surgery, Affiliated Hospital of Putian University, Putian, China 2Department of Bariatric Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China 3Department of Anaesthesia, The First Hospital of Putian City, Putian, Fujian, China 4The Department of General Surgery, The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China 5Department of General Practice, Affiliated Hospital of Putian University, Putian, China...