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Shari Barnett on Muck Rack

Shari Barnett

As seen in: Nature
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Articles

Identification of isoform switching events linked with esophageal adenocarcinoma patient survival informs novel prognostic and therapeutic targets

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By Yun Zhang, Jean-Jack Riethoven, Jennifer Clarke, Kiran H. Lagisetty, Jules Lin, Rishindra M. Reddy, Andrew Chang, David D. Odell, Analisa Difeo, Maureen A. Sartor, David A. Ntsiful, Bryce Vandenburg, Shari Barnett, Laura A. Kresty
| Nature Verified
Abstract Esophageal adenocarcinoma (EAC), the dominant subtype of esophageal cancer in developed countries, is a growing health problem, characterized by poor patient prognosis and dismal survival due to ineffective screening tools and a lack of efficacious options targeting the interception or treatment of EAC. Despite molecular advances, molecular targeting of EAC remains elusive, suggesting the need for identifying alternative targets with improved prognostic and therapeutic value.
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