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Shawn A. Abeynaike on Muck Rack

Shawn A. Abeynaike

As seen in: MDPI, BioRxiv
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Articles

TRAIL-mediated PMN-MDSC depletion prevents CD4+ T cell loss in HIV-infected humanized mice

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By Silke Paust, Shawn A. Abeynaike, Kayla Frank, Angel Gandarilla
| BioRxiv
Abstract Myeloid derived suppressor cells (MDSCs) are critical regulators of HIV immunity, but the mechanisms behind their expansion and value as a therapeutic target remain unclear. We investigated MDSC function in HIV using a humanized mouse model. Acute HIV-1 infection triggered the systemic expansion of polymorphonuclear MDSCs (PMN-MDSCs), with their frequency correlating positively with plasma viral load.
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Human Hematopoietic Stem Cell Engrafted IL-15 Transgenic NSG Mice Support Robust NK Cell Responses and Sustained HIV-1 Infection

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By Shawn A. Abeynaike, Tridu R. Huynh, Abeera Mehmood, Teha Kim
| MDPI
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Shawn A. Abeynaike 1, Tridu R.
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