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Shawnta Y. Chaney on Muck Rack

Shawnta Y. Chaney

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SLC16A8 is a causal contributor to age-related macular degeneration risk - npj Genomic Medicine

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By Charles C. Wykoff, Ehsan Ullah, Emily Y. Chew, Wadih M. Zein, Mark McCarthy, Jeffrey Hofmann, Shawnta Y. Chaney
| Nature Verified
Abstract Age-related macular degeneration (AMD), a complex neurodegenerative disease, is a leading cause of visual impairment worldwide with a strong genetic component. Genetic studies have identified several loci, but few causal genes with functional characterization. Here we highlight multiple lines of evidence which show a causal role in AMD for SLC16A8, which encodes MCT3, a retinal pigment epithelium (RPE) specific lactate transporter.
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