Shayan Ali Irfan on Muck Rack

Shayan Ali Irfan

As seen in: Multiple Sclerosis and Related Disorders
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Articles

Clinical audit: reviewing management of gallbladder and common bile duct stones at a public sector tertiary care hospital in Karachi, Pakistan

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By Shayan Ali Irfan, Anusha Ashkar, Imrana Zulfikar
| jpma.org.pk
Objectives: To evaluate adherence to the guidelines for the management of gallstones in a tertiary care setting. Methods: The clinical audit was conducted at the General Surgical Unit VI, Civil Hospital, Karachi, and comprised data of laparoscopic cholecystectomy from October 1 to November 1, 2023. Management practices were assessed using the guidelines published by the National Institute of Health and Care Excellence.
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PROMISING ROLE OF TEMELIMAB IN MULTIPLE SCLEROSIS TREATMENT

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By Shayan Ali Irfan, Minha Murtaza, Ali Ahmed, Hina Altaf
| Multiple Sclerosis and Related Disorders Verified
HIGHLIGHTS • Multiple sclerosis involves immune-mediated demyelination of nerve fibers and neurons leading to permanent nerve damage. • Role of MS-associated envelope protein (MSRV-Env) is suggested in the pathogenesis of MS. • Temelimab is a humanized IgG4 monoclonal antibody (mAb) that targets the MSRV-Env protein. • Clinical trials demonstrate that the drug is safe as well as favourable for use in MS patients.
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