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Shaying Zhao on Muck Rack

Shaying Zhao

As seen in: Wiley Online Library, BioRxiv
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Articles

Initial Characterization of Canine T-cell Receptor Repertoires Using RNA-seq Data from Different Diseases and Tissues

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By Mengyuan Zhang, Kun-Lin Ho, Shaying Zhao
| BioRxiv
Abstract The dog serves as a key translational model in cancer immunotherapy. Understanding the T cell receptor (TCR) repertoire is needed for various cancer immunotherapies. Compared to humans where >300 million TCRs have been identified, <100 canine TCRs are reported.
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Leading the pack: Best practices in comparative canine cancer genomics to inform human oncology

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By Cheryl London, Heather Gardner, Shaying Zhao
| Wiley Online Library Verified
1 INTRODUCTION Mouse models of cancer have been instrumental for dissecting biological processes that underlie tumorigenesis. However, these often lack key features of spontaneous disease including treatment-induced resistance and multi-focal metastases that sometimes occurs a decade or longer post therapy.
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