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Articles

A multi-gene expression profile panel for predicting liver metastasis: An algorithmic approach

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By Rakesh Rawal, Kanisha Shah, Shanaya Patel, Sheefa Mirza
| PLOS
The expression profile of all the 15 genes were subjected to PCA and LDA analysis and 5 models were generated. ROC curve analysis was performed for all the models and the individual genes. It was observed that out of the 15 genes only 8 genes showed significant sensitivity and specificity. Another model consisting of the selected eight genes was generated showing a specificity and sensitivity of 90.0 and 96.87 respectively (p <0.0001).
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