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Chemical characterization of Dicliptera bupleuroides aerial parts and evaluation of its anti‐inflammatory potential in vitro, in vivo and in silico
This study aimed to evaluate the anti-inflammatory activity of Dicliptera bupleuroides methanol extract (DBM) and its fractions. The samples showed significant inhibition of cyclooxygenase where DBM showed the highest inhibitory potential at 100 µg/mL estimated by 67.86%.. At a 400 mg/kg dose, all the samples showed pronounced results in carrageenan induced acute inflammation in rat model with DBM showed the highest efficiency displaying 65.32% inhibition compared to the untreated rats.
Targeting Anti-Inflammatory Pathways to Treat Diabetes-Induced Neuropathy by 6-Hydroxyflavanone
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