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Abstract Temporomandibular joint osteoarthritis (TMJ-OA) causes chronic pain, cartilage degeneration and pathological neurovascular remodeling, yet effective local therapies remain limited. Here we develop a minimally invasive near-infrared (NIR)-responsive microneedle system (SFZICC MNs) that integrates cryptochlorogenic acid (CCA)- and carbon quantum dot-loaded ZIF-8 nanoparticles within a methacrylated silk fibroin hydrogel.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.