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Nanotechnology-leveraged CRISPR/Cas systems: icebreaking in trace cancer-related nucleic acids biosensing - Molecular Cancer
Cancer is the leading cause of death worldwide. The World Health Organization (WHO) reports that cancer is responsible for nearly 10 million deaths annually, making up one-sixth of all deaths [1]. It is reported that most cancers are asymptomatic in the early stages, and 50% of them still only detected at an advanced stage [2], which seriously endanger human life and health. Thus, it is imperative to achieve their early detection [3]. As shown in Fig.
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